Tan simple cómo especificar la cancelación de edición y eliminación suscribiéndote a estos eventos del control:
Saludos
Código (vbnet) [Seleccionar]
Dim enableReadOnly As Boolean = True
''' <summary>
''' Handles the <see cref="RadListView.ItemEditing"/> and <see cref="RadListView.ItemRemoving"/> events of the <see cref="RadListView1"/> control.
''' </summary>
''' <param name="sender">The source of the event.</param>
''' <param name="e">The <see cref="Telerik.WinControls.UI.ListViewItemCancelEventArgs"/> instance containing the event data.</param>
Private Sub RadListView1_ItemEditing_Or_ItemRemoving(ByVal sender As Object, ByVal e As ListViewItemCancelEventArgs) _
Handles RadListView1.ItemEditing,
RadListView1.ItemRemoving
e.Cancel = Me.enableReadOnly
End Sub
Saludos